C-CEE 110_604 Upgrade support package from 21 to 28

Hi Gurus,

Im using ERP ECC 6.06 with SAP_BASIS 731 SP5, SAP_APPL 606 SP5,

and planning to upgrade component C-CEE 110_604 support package from 21 to 28.

can we directly using SPAM ? any per-requisite that need to take concern

please advise.

Thanks

Regards

Lowis